Disodium salt of EDTA is widely accepted across as sequestering / chelating agent, that helps in cleaning and descaling of all acid insoluble sulphates of calcium, barium and strontium, as well as calcium fluorides. Also, it finds extensive usage in removal of iron oxide/hydroxide and calcium carbonate, and if used in synergistic blend with alkaline cleaners, it can also help in removal of organic substances and microbial slimes.
There are many kinds of blood anticoagulants in blood collection reagents, and one anticoagulant is widely used, that is EDTA potassium salt. EDTA potassium salt has a variety of models, in which potassium is used more, but how about its principle and application? There should be some people who don't know it very well. Here we can look at its application fields and principles.
EDTA dipotassium salt, also known as EDTA-K2 dihydrate, is a white crystalline powder, easily soluble in water and hygroscopic, with a molecular weight of 404.6. Deta dipotassium salt can protect blood cell composition, does not affect white blood cells, has the least impact on red blood cells, and can inhibit platelet aggregation, which is suitable for general blood test. However, apart from platelet separation test, it is not suitable for coagulation test and platelet kinetic energy test, nor for determination of calcium, potassium, sodium, iron, alkaline phosphatase, creatine kinase, leucine aminopeptidase and PCR test.
EDTA dipotassium salt as anticoagulant principle, first we understand the principle of blood coagulation, and this can be divided into three parts, 1, the formation of prothrombin activator, 2, prothrombin activator in the presence of calcium ion to make prothrombin into active thrombin, 3, soluble fibrinogen in the role of thrombin into insoluble fibrin. Fibrin is like filaments, crisscross, and contains a large number of blood cells to form a jelly like blood clot. This is what happens to blood clotting. EDTA ions in the blood can be converted into calcium antithrombin, so that the blood has a great affinity for calcium.
Cas No.65501-24-8
Usage: Desheng EDTA salt can protect the cellular components of blood, does not affect the cell morphology, and inhibits the aggregation of platelets. It is suitable for general hematological tests.
Characteristics:
1. Desheng has a professional R&D team for EDTA K3, which can give professional responses in time for the use and problems of EDTA K3, and can also customize the production of special indicators.
2. Desheng has long-term stock of EDTA tripotassium, which can be delivered immediately and meet the needs of large goods;
3. The EDTA tripotassium produced by Desheng has been sold to more than 300 customers at home and abroad, with a professional foreign trade team and rich export experience.
Production Process of Tripotassium EDTA:
Raw material-Feeding-Adjusting-Concentrating-Output-Crystallization-Drying-Crushing-Packing-Warehouse
Tetrasodium EDTA is an amino acidic chelating agent minimizing metal ion contamination and facilitating enzymatic reactions that could be inhibited by heavy metal traces. EDTA Tetrasodium salt also works as a slime dispersant and is even effective in reducing scale deposits and water hardness.
