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Siddharth Carbochem Products Ltd.

Supplier From India
Feb-19-16
Supplier : Methyl salicylate, octyl salicylate, homosalicylate, salicylic acid, sodium salicylate

Established: 1985 Standards: ISO, GMP

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Contact Details:
Eros Theatre Bldg., J. Tata Road, Churcg
Mumbai 400020
Maharashtra India


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Molecular Formula - C7H6O3
Molecular Weight - 138.12
Appearance - white crystalline powder
Density - 1.44g/cm3
Melting point - 158-161 C
Boiling point - 211 C (20 mmHg)
Assay - 99.0% min
Loss on drying - 0.5%max
Application - Pharmaceutical Intermediate
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Salicylic acid is a colorless, organic compound with the chemical formula C7H6O3, renowned for its widespread applications in skincare and medicine. It is a beta hydroxy acid (BHA) with properties that make it effective for exfoliating and treating various skin conditions. In skincare, salicylic acid is used to treat acne by unclogging pores and reducing inflammation. It is also employed for its keratolytic properties, which help remove dead skin cells, making it valuable for treating conditions like psoriasis, warts, and calluses. In medicine, salicylic acid has historically been used for pain relief and fever reduction, and it is the precursor to aspirin. Its ability to address a range of skin concerns and its medical applications underscore its significance in both personal care and healthcare fields.
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Sodium Salicylate is a shiny, white powder with sweetish taste and mild aromatic aroma that is soluble in water, glycerol, and alcohol. Used in medicine and as a preservative and as an analgesic and antipyretic agent. It also acts as non-steroidal anti-inflammatory drug (NSAID) in Aspirin, and induces apoptosis in cancer cells and also necrosis. USP, or United States Pharmacopeia, grade chemicals comply with the standards of the United States Pharmacopeia and National Formulary (USP-NF). USP Grade chemicals are fit for use in food, drugs, and medicines. They are subject to stringent testing and are typically required to have the highest level of purity.
Specifications

Assay: 99.50 % 100.50 % (on the anhydrous basis)
Description: Amorphous or microcrystalline powder or scales, is colorless or has no more than a faint pink tinge. Is odorless or has a faint characteristic odor and is affected by light.
Solubility: Freely and slowly soluble in water and in glycerin; very soluble in boiling water and in boiling alcohol; slowly soluble in alcohol
Water: < 0.50 %
Sulfite or Thiosulfate: < 0.15 ml of 0.1N iodine
Heavy Metals: < 20 ppm
Residual Solvents: Should meet the requirements

Identification Test
A) Infrared Absorption: IR absorption spectrum of the preparation of the test specimen exhibits maxima only at the same wavelength as that of a similar preparation of the corresponding USP reference standard
B) Salicylate and Sodium: Sample solution: 50 mg/ml of sodium and salicylate in water. Acceptance criteria: meets the requirement

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Salicylic Acid USP is used in pharmaceutical industries as well as its used in a great number of cosmetic applications for acne and oily skin as a chemical exfoliant It works as a keratolytic and comedolytic agent It is in many skin care products and dandruff shampoos It is also used as an intermediate in the production of agrochemical products dyes and colorants as well as in the rubber industry and in the manufacture of phenolic resins
Sales Specifications

Assay 9800 10200 dry basis
Description White crystals usually in fine needles or a fluffy white crystalline powder Has a sweetish followed by an acrid taste and is stable in air
Solubility Freely soluble in alcohol and in ether soluble in boiling water sparingly soluble in chloroform slightly soluble in water and in benzene
Residue on ignition 005 003
Chloride 0014
Sulphate 002
Loss on drying 050

Organic Impurities
4Hydroxybenzoic Acid 010
4Hydroxyisothalic Acid 005
Phenol 002
Other impurity 005
Total impurities 020

Identification
A By IR Conforms
B The retention time of the major peak of the sample solution corresponds to that of a standard solution as obtained in the assay
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Packing

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