Sodium methanolate, also known as sodium methylate, is an organic compound with the formula NaOCH3. It is a white, hygroscopic solid that is soluble in methanol and other polar solvents. Sodium methanolate is primarily used as a strong base in organic synthesis, where it plays a crucial role in various chemical reactions. The compound is a derivative of methanol, where the hydroxyl group (-OH) is replaced by a sodium atom, resulting in a highly reactive species.
The discovery of sodium methanolate can be traced back to the mid-20th century, during a period of increased interest in the development of efficient chemical reagents. Researchers were exploring methods to produce alkoxides, which are essential intermediates in organic synthesis. The synthesis of sodium methanolate is typically achieved by reacting sodium metal with methanol, a straightforward process that produces sodium methanolate along with hydrogen gas. This method exemplifies a classic approach to generating alkoxides from their corresponding alcohols.
In organic chemistry, sodium methanolate serves as a powerful nucleophile and base. It is widely employed in the synthesis of various organic compounds, particularly in the preparation of esters, ethers, and other functionalized molecules. One of its notable applications is in the transesterification reaction, where it catalyzes the conversion of triglycerides into biodiesel. This process involves the reaction of triglycerides with methanol, leading to the production of fatty acid methyl esters and glycerol. Sodium methanolate's efficiency in this reaction has made it a preferred choice in biodiesel production, contributing to the growing interest in renewable energy sources.
In addition to its role in biodiesel synthesis, sodium methanolate is also used in the production of pharmaceuticals and agrochemicals. Its ability to facilitate nucleophilic substitutions makes it an important reagent in the synthesis of various bioactive compounds. Furthermore, sodium methanolate is utilized in polymer chemistry, particularly in the preparation of poly(methyl methacrylate) (PMMA) and other methacrylate-based polymers, which are widely used in coatings, adhesives, and medical devices.
Safety considerations are paramount when handling sodium methanolate. It is a highly reactive and flammable substance that can cause skin and eye irritation upon contact. Proper personal protective equipment (PPE), including gloves and goggles, is essential during its use. Additionally, due to its hygroscopic nature, sodium methanolate should be stored in a dry environment to prevent degradation and moisture absorption.
Brand: Soarwin
CAS No.: 124-41-4
EC number:204-699-5
Molecular Formula: CH3NaO
Density: 0.97g/mLat 20°C
Boiling point:65 °C
Melting point:-98 °C
Flashing point: 11 °C
