Paraformaldehyde is a polymer of formaldehyde with the chemical formula (CH2O)n, where n is typically in the range of 8 to 100. It is a white, crystalline solid composed of small, polymeric formaldehyde units. Paraformaldehyde is commonly used as a solid form of formaldehyde, and it has various applications in different fields.
Form and Structure:
Paraformaldehyde is a low-molecular-weight polymer of formaldehyde, consisting of repeating CH2O units.
It is often produced in the form of white, crystalline granules or as a powder.
Uses:
Fixative in Histology: Paraformaldehyde is commonly used in histology and pathology laboratories as a fixative for preserving biological specimens for microscopic analysis.
Disinfectant: It has disinfectant properties and can be used for sterilizing equipment.
Crosslinking Agent: Paraformaldehyde is used in the crosslinking of proteins, peptides, and nucleic acids in molecular biology applications.
Chemical Synthesis: It serves as a source of formaldehyde in various chemical reactions and syntheses.
Handling and Safety:
Paraformaldehyde should be handled with care, and precautions should be taken to avoid inhalation, skin contact, or ingestion.
When paraformaldehyde is heated, it releases formaldehyde gas, which is a strong irritant. Adequate ventilation and protective equipment should be used when working with paraformaldehyde.
Dissolution:
To use paraformaldehyde as a fixative or in other applications, it is typically dissolved in water to generate a formaldehyde solution.
Storage:
Paraformaldehyde should be stored in a cool, dry place away from heat sources and incompatible materials.
