ADVAPD Suture is synthetic absorbable sterile surgical suture composed of a copolymer made from polyester and Polydioxanone.

The advanced extrusion process of the molecule of Polydioxanone gives ADVAPD:

ADVAPD Suture is indicated for use in soft tissue approximation, including use in pediatric cardiovascular tissue where growth is expected to occur and ophthalmic surgery. PDS II Suture is not indicated in adult cardiovascular surgery, microsurgery and neural tissue.

ADVAPD Suture is particularly useful where the combination of an absorbable suture and extended wound support (up to six weeks) is desirable.

ADVAPD Suture, being absorbable, is not to be used where prolonged (beyond six weeks) approximation of tissues under stress is required and is not to be used in conjunction with prosthetic devices (i.e. heart valves or synthetic grafts). Suture absorption occurs by means of hydrolysis. Absorption begins as a loss of tensile strength followed by a loss of mass.