Alpha-Cyclodextrin is produced by the action of cyclodextrin glucosyltransferase (CGTase, EC 2.4.1.19) on hydrolysed starch syrups at neutral pH (6.0-7.0) and moderate temperature (35-40�°C).
The annular (or doughnut-shaped) structure of alpha-cyclodextrin provides a hydrophobic cavity that allows formation of inclusion complexes with a variety of non-polar organic molecules of appropriate size.
The hydrophilic nature of the outer surface of the cyclic structure makes alpha-cyclodextrin water-soluble.
Function Application
-Alpha-Cyclodextrin is used to increase the stability of the material:Prevent volatilization, prevent
sublimation; Anti-oxidation;
-Alpha-Cyclodextrin is used to prevent optothermal decomposition; Anti chemical decomposition; Extend the period of validity of the material.
-Alpha-Cyclodextrin is used to increase the material solubility and bioavailability.
-Through the formation of inclusion complex to achieve effective cover excitant odour.
-Liquid drug into solid state.
-Alpha-Cyclodextrin is used to prevent drug - drug, drug - interaction between additive.
-Alpha-Cyclodextrin is used to reduce side effects.
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